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Asymmetric hydrolyses of 1,2‐ and 1,3‐diacetoxycyclohexanes with the cultured suspension cells of Marchantia polymorpha
Author(s) -
Hirata Toshifumi,
Izumi Shunsuke,
Aoki Masahiro,
Gotoh Shisei,
Utsumi Ryoichi
Publication year - 1997
Publication title -
chirality
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.43
H-Index - 77
eISSN - 1520-636X
pISSN - 0899-0042
DOI - 10.1002/(sici)1520-636x(1997)9:3<250::aid-chir8>3.0.co;2-j
Subject(s) - chemistry , stereocenter , hydrolysis , stereochemistry , chirality (physics) , suspension (topology) , suspension culture , cell culture , biochemistry , catalysis , enantioselective synthesis , biology , pure mathematics , genetics , mathematics , homotopy , chiral symmetry breaking , physics , quantum mechanics , quark , nambu–jona lasinio model
Very high enantioselectivities were observed in the hydrolysis of racemic 1,2‐ and 1,3‐diacetoxycyclohexanes and their derivatives by cultured cells of Marchantia polymorpha in suspension. Asymmetry was also induced in the hydrolyses of meso ‐1,2‐ and 1,3‐diacetates to the corresponding monoacetates. These findings indicate that these cultured cells hydrolyze the acetoxyl groups enantioselectively at the stereogenic center of R‐configuration. Chirality 9:250–253, 1997. © 1997 Wiley‐Liss, Inc.