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Enantiomeric resolution by HPLC of axial chiral amides using amylose tris[(S)‐1‐phenylethylcarbamate]
Author(s) -
Cass Quezia B.,
Degani Ana Luiza G.,
Tiritan M. Elizabeth,
Matlin Stephen A.,
Curran Dennis P.,
Balog Aaron
Publication year - 1997
Publication title -
chirality
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.43
H-Index - 77
eISSN - 1520-636X
pISSN - 0899-0042
DOI - 10.1002/(sici)1520-636x(1997)9:2<109::aid-chir6>3.0.co;2-c
Subject(s) - chemistry , enantiomer , tris , amylose , resolution (logic) , particle size , cellulose , chromatography , chiral resolution , organic chemistry , starch , biochemistry , artificial intelligence , computer science
The enantiomeric resolution of a series of N‐arylamides was examined on amylose tris[(S)‐1‐phenylethylcarbamate] coated onto aminopropylated 7 μm silica with 500 Å diameter pores and on naked silica 5 μm particle size with 500 Å diameter pores. The enantiomeric resolution obtained for this series was excellent on both columns. The enantioselectivity of cellulose and amylose tris (3,5‐dimethylphenylcarbamate) coated onto APS‐Hypersil (120 Å pore size, 5 μm particle size) was also investigated for this series of compounds. Chirality 9:109–112, 1997. © 1997 Wiley‐Liss, Inc.