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Optical resolution by preferential crystallization of DL ‐methionine hydrochloride
Author(s) -
Shiraiwa Tadashi,
Miyazaki Hideya,
Watanabe Takahiro,
Kurokawa Hidemoto
Publication year - 1997
Publication title -
chirality
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.43
H-Index - 77
eISSN - 1520-636X
pISSN - 0899-0042
DOI - 10.1002/(sici)1520-636x(1997)9:1<48::aid-chir9>3.0.co;2-c
Subject(s) - chemistry , crystallization , triethylamine , chirality (physics) , hydrochloride , methionine , melting point , solubility , resolution (logic) , nuclear chemistry , organic chemistry , amino acid , biochemistry , chiral symmetry , physics , quantum mechanics , artificial intelligence , computer science , nambu–jona lasinio model , quark
DL ‐Methionine hydrochloride ( DL ‐Met·HCl) was found to exist as a conglomerate, based on the infrared spectrum, solubility, and melting point. The optical resolution of DL ‐Met·HCl was successfully achieved by preferential crystallization into D ‐and L ‐Met·HCl. Treatment of the purified D ‐ and L ‐Met·HCl with triethylamine gave D ‐ and L ‐methionine of 100% optical purities. Chirality, 9;48–51, 1997. © 1997 Wiley‐Liss, Inc.