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Signal transduction pathways regulating the contraction of an insect visceral muscle
Author(s) -
Lange Angela B.,
Nykamp David A.
Publication year - 1996
Publication title -
archives of insect biochemistry and physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.576
H-Index - 66
eISSN - 1520-6327
pISSN - 0739-4462
DOI - 10.1002/(sici)1520-6327(1996)33:3/4<183::aid-arch2>3.0.co;2-u
Subject(s) - locust , biology , calmodulin , signal transduction , second messenger system , microbiology and biotechnology , muscle contraction , biochemistry , neuroscience , endocrinology , enzyme , botany
This review examines the signal transduction pathways which regulate the contraction of an insect visceral muscle, namely the oviduct of the locust, Locusta migratoria . Detailed studies based upon neurophysiology, neurochemistry, and neuropharmacology have defined the neural control over contraction of locust oviducts. The identification of a variety of neuroactive chemicals which are associated with the innervation of this muscle, including peptides, an amine, and an amino acid, has allowed examination of second messenger systems which lead to an intricate control over muscle contraction. Thus, it is known that these neuroactive chemicals are involved with G‐proteins, membrane lipid systems, cyclic nucleotides, calcium, and calmodulin as well as protein phosphorylation, thereby allowing these extracellular neuroactive chemicals to initiate and modulate contractile events within the individual muscle cells. Each of these systems is reviewed in the context of locust oviduct contraction and the possibilities of cross‐talk regulation between these second messengers discussed. © 1996 Wiley‐Liss, Inc.