Premium
Absence of the alpha‐1‐antitrypsin PI*Z allele in Tunisia substantiates the particular genetic structure of African populations
Author(s) -
Makni S.,
Zitouni M.,
Ayed K.,
Mhirii S.,
Azabi S.,
Cherif F.,
Maalej M.,
Martin J.P.,
Sesboüé R.
Publication year - 1997
Publication title -
american journal of human biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.559
H-Index - 81
eISSN - 1520-6300
pISSN - 1042-0533
DOI - 10.1002/(sici)1520-6300(1997)9:2<223::aid-ajhb8>3.0.co;2-0
Subject(s) - hum , allele , pi , alpha (finance) , genetics , phenotype , biology , allele frequency , incidence (geometry) , genotype , gene , medicine , history , physics , biochemistry , construct validity , nursing , performance art , optics , patient satisfaction , art history
Alpha‐1‐antitrypsin (PI) phenotypes were studied in a sample of 450 Tunisians. The observed frequencies of PI alleles were identical to those in African populations, with a very low incidence of PI*S and virtual absence of PI*Z. Such figures are similar to estimates in Asians and clearly opposite to those in Europeans. Am. J. Hum. Biol. 9:223–224, 1997. © 1997 Wiley‐Liss, Inc.