Open AccessSingle Molecule Detection in Life Sciences
Author(s) -
Ishii Yoshiharu,
Yanagida Toshio
Publication year - 2000
Publication title -
single molecules
Language(s) - English
Resource type - Journals
eISSN - 1438-5171
pISSN - 1438-5163
DOI - 10.1002/(sici)1438-5171(200004)1:1<5::aid-simo5>3.0.co;2-a
Subject(s) - biomolecule , computational biology , nanotechnology , dna , molecule , biophysics , chemistry , biology , materials science , biochemistry , organic chemistry
In recent years, the development of single molecule detection (SMD) techniques has opened up a new era of life science. The dynamic properties of biomolecules and the unique operations of molecular machines, which were hidden in averaged ensemble measurements, have been unveiled. The SMD techniques have rapidly been expanding to include a wide range of life science. The experiments on molecular motors, DNA transcription, enzyme reactions, protein dynamics, and cell signaling are summarized in this short review.