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Cellular proteins in HIV virions
Author(s) -
Ott David E.
Publication year - 1997
Publication title -
reviews in medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.06
H-Index - 90
eISSN - 1099-1654
pISSN - 1052-9276
DOI - 10.1002/(sici)1099-1654(199709)7:3<167::aid-rmv199>3.0.co;2-k
Subject(s) - virology , human immunodeficiency virus (hiv) , computational biology , biology , medicine
Human immunodeficiency virus type‐1 (HIV‐1) virions contain both virus‐encoded and cellular proteins. Recent advances in the detection, isolation, and functional characterisation of host proteins incorporated in the virion have begun to provide for new perspectives on the interactions between virus and cell. The acquisition of host proteins by HIV‐1 may also influence viral pathology in vivo . This article reviews detection and analysis of host proteins found in HIV‐1 particles and presents some potential roles that these proteins might play in the biology of this important virus. © 1997 John Wiley & Sons, Ltd.