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The in vitro effect of dandelions antioxidants on microsomal lipid peroxidation
Author(s) -
Hagymási K.,
Blázovics A.,
Fehér J.,
Lugasi A.,
Kristó Sz. T.,
Kéry Á.
Publication year - 2000
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/(sici)1099-1573(200002)14:1<43::aid-ptr522>3.0.co;2-q
Subject(s) - lipid peroxidation , choleretic , microsome , antioxidant , pharmacognosy , chemistry , pharmacology , in vitro , biochemistry , biological activity , drug , diuretic , traditional medicine , biology , medicine
Dandelions have long been used in herbal medicine for their choleretic, diuretic, antiinflammatory, appetite‐stimulating and laxative properties. An antioxidant property can be supposed as a basis of theirtherapeutic effects. To understand the mechanism of the drug's action, the effects of natural extracts on a microsomal fraction of rat liver were examined. The extracts diminished the enzymatically inducedlipid peroxidation and reduced the cytochrome c with and without NADPH in a concentration dependent manner. Copyright © 2000 John Wiley & Sons, Ltd.