Premium
In vitro antitrypanosomal activity of Moringa stenopetala leaves and roots
Author(s) -
Mekonnen Yalemtsehay,
Yardley Vanessa,
Rock Peter,
Croft Simon
Publication year - 1999
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/(sici)1099-1573(199909)13:6<538::aid-ptr486>3.0.co;2-k
Subject(s) - amastigote , traditional medicine , biology , trypanosoma cruzi , trypanosoma brucei , in vitro , acetone , moringa , pharmacognosy , botany , parasite hosting , food science , biological activity , biochemistry , leishmania , medicine , world wide web , computer science , gene
The leaves and the root extracts of Moringa stenopetala were tested in vitro against trypomastigotes of Trypanosoma brucei, Trypanosoma cruzi and L. donovani amastigotes. The fresh root wood ethanol extract and the dried leaves acetone extract were found to be active against T. brucei with an ED 50 value of 9.2 µg/mL and 10.0 µg/mL respectively. All the other extracts were inactive against all the tested parasite forms. Copyright © 1999 John Wiley & Sons, Ltd.