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Hepatoprotective activity of Ficus racemosa leaf extract on liver damage caused by carbon tetrachloride in rats
Author(s) -
Mandal Subhash C.,
Maity Tapan K.,
Das J.,
Pal M.,
Saha B. P.
Publication year - 1999
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/(sici)1099-1573(199908/09)13:5<430::aid-ptr456>3.0.co;2-g
Subject(s) - moraceae , carbon tetrachloride , ficus , alkaline phosphatase , bilirubin , traditional medicine , pharmacognosy , liver function , chemistry , ccl4 , liver damage , medicine , botany , biology , biochemistry , biological activity , enzyme , in vitro , organic chemistry
An extract of the leaves of Ficus racemosa Linn. (Moraceae) was evaluated for hepatoprotective activity in rats by inducing chronic liver damage by subcutaneous injection of 50% v/v carbon tetrachloride in liquid paraffin at a dose of 3 mL/kg on alternate days for a period of 4 weeks. The biochemical parameters SGOT, SGPT, serum bilirubin and alkaline phosphatase were estimated to assess the liver function. The activity of extract was also comparable to a standard liver tonic (Neutrosec). Copyright © 1999 John Wiley & Sons, Ltd.