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Antioxidant activity of flavonoids from Solanum melongena
Author(s) -
Sudheesh S.,
Sandhya C.,
Sarah Koshy Asha,
Vijayalakshmi N. R.
Publication year - 1999
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/(sici)1099-1573(199908/09)13:5<393::aid-ptr474>3.0.co;2-8
Subject(s) - melongena , solanum , antioxidant , traditional medicine , pharmacognosy , flavonoid , solanaceae , biology , botany , medicine , biological activity , in vitro , biochemistry , gene
Flavonoids isolated from Solanum melongena (brinjal) showed potent antioxidant activity. Concentrations of malondialdehyde, hydroperoxides and conjugated dienes were lowered significantly. The activity of catalase was found to be significantly enhanced in the tissues of normal and cholesterol fed rats administered 1 mg flavonoid from brinjal/100 g BW/day. The concentration of glutathione also showed elevated values in the experimental animals. The elevated levels of glutathione and significantly stimulated activity of catalase may be responsible for the antioxidant effect of these flavonoids. Copyright © 1999 John Wiley & Sons, Ltd.