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Antiinflammatory activity of some extracts from plants used in the traditional medicine of North‐African countries (II)
Author(s) -
Rimbau Victor,
Cerdan Cristina,
Vila Roser,
Iglesias Josep
Publication year - 1999
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/(sici)1099-1573(199903)13:2<128::aid-ptr399>3.0.co;2-7
Subject(s) - traditional medicine , chloroform , carrageenan , arachidonic acid , folk medicine , medicinal plants , pharmacognosy , aqueous extract , dose dependence , chemistry , pharmacology , biology , botany , medicine , biological activity , biochemistry , in vitro , chromatography , enzyme
Aqueous, ethanol and chloroform extracts from Corrigiliola telephiifolia, Echinops spinosus, Kundmania sicula, Tamarindus indica and Zygophyllum gaetulum were evaluated for antiinflammatory properties in mice (ear oedema induced by arachidonic acid) and rats (subplantar oedema induced by carrageenan) after topical or i.p. administration, respectively. Our results showed that all the plants exhibit antiinflammatory activity, since at least one extract from each plant was active in one of the experimental models. Whereas all the extracts of Corrigiliola telephiifolia and Echinops spinosus were highly active on all the experimental models assayed (values of inflammation inhibition well above 50%), poorer activity profiles were recorded in Kundmania sicula, Tamarindus indica and Zygophyllum gaetulum. These results support the traditional uses for these plants but indicate that the active principles in the chloroform extracts are probably more active and/or are contained in larger concentrations than the principles in the polar extracts used in the traditional medicine of North‐African countries. Copyright © 1999 John Wiley & Sons, Ltd.