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Evaluation of the analgesic action of different fractions from the methanol extract of Teucrium buxifolium L
Author(s) -
Beltrán B.,
Bello R.,
Calatayud S.,
Moreno L.,
PrimoYúfera E.,
Esplugues J.
Publication year - 1998
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/(sici)1099-1573(199812)12:8<598::aid-ptr361>3.0.co;2-#
Subject(s) - teucrium , analgesic , methanol , pharmacognosy , fraction (chemistry) , chemistry , traditional medicine , extraction (chemistry) , biological activity , pharmacology , chromatography , medicine , in vitro , lamiaceae , biochemistry , organic chemistry
Different fractions (F‐2, F‐3, F‐5) of the methanol extract from Teucrium buxifolium L. have been tested for their analgesic activity in mice. All of them exhibited peripheral analgesic activity except F‐3. Fraction F‐5 had the strongest effect and was subjected to a second re‐extraction. The subfractions obtained (F‐5/3 and F‐5/8) exhibited a similar activity to that observed with the whole fraction. Copyright © 1998 John Wiley & Sons, Ltd.