Premium
Inhibitory effect of the methanol extracts from compositae plants on 12‐ O ‐tetradecanoylphorbol‐13‐acetate‐induced ear oedema in mice
Author(s) -
Yasukawa Ken,
Akihisa Toshihiro,
Inoue Youhei,
Tamura Toshitake,
Yamanouchi Sakae,
Takido Michio
Publication year - 1998
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/(sici)1099-1573(199811)12:7<484::aid-ptr341>3.0.co;2-l
Subject(s) - chrysanthemum morifolium , dandelion , helianthus annuus , taraxacum officinale , pharmacognosy , traditional medicine , biology , botany , 12 o tetradecanoylphorbol 13 acetate , sunflower , biological activity , horticulture , biochemistry , medicine , enzyme , in vitro , phorbol ester , alternative medicine , pathology , traditional chinese medicine , protein kinase c
We report that the extracts of Compositae plants inhibit 12‐ O ‐tetradecanoylphorbol‐13‐acetate (TPA)‐induced ear oedema in mice. Seventy five methanol extracts obtained from 53 species in 11 tribes of Compositae plants were assayed and their inhibitory ratios calculated. In general, medicinal and edible plant extracts were more effective inhibitors than those from other materials, and the flower extracts were more effective inhibitors than those from other parts. The methanol extracts of the flowers of Cirsium arvense, Taraxacum officinale and T. platycarpum (dandelion), Chrysanthemum morifolium var. sinensis forma esculentum (edible chrysanthemum), C. nipponicum, Matricaria matricarioides and Helianthus annuus (sunflower) markedly inhibited the inflammation induced by TPA in mice. Copyright © 1998 John Wiley & Sons, Ltd.