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The effects of Morinda lucida Benth (Rubiaceae) extract on the gastrointestinal tract of rodents
Author(s) -
Olajide O. A.,
Awe S. O.,
Makinde J. M.
Publication year - 1998
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/(sici)1099-1573(199809)12:6<439::aid-ptr319>3.0.co;2-p
Subject(s) - rubiaceae , gastric emptying , motility , traditional medicine , pharmacognosy , gastrointestinal tract , phytotherapy , stomach , intestinal motility , gastric acid , biology , medicine , pharmacology , gastroenterology , biological activity , botany , in vitro , biochemistry , pathology , genetics , alternative medicine
The dried methanol extract of the leaves of Morinda lucida Benth was studied for its effects on gastric emptying in rats and intestinal motility in mice. The effect of the extract on acetylsalicylic acid‐induced gastric ulcer in rats was also investigated. The extract promoted gastric emptying time in rats and intestinal motility in mice. The extract did not induce gastric ulceration in rats and failed to protect against acetylsalicylic acid‐induced ulcer in rats. © 1998 John Wiley & Sons, Ltd.