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Immunomodulatory activities of Trichilia glabra leaf aqueous extracts
Author(s) -
Benencia Fabián,
Coulombié Félix C.
Publication year - 1998
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/(sici)1099-1573(199805)12:3<167::aid-ptr213>3.0.co;2-y
Subject(s) - pharmacognosy , traditional medicine , aqueous solution , biology , chemistry , botany , medicine , biological activity , in vitro , biochemistry
Human peripheral blood monocytes and polymorphonuclear leukocytes treated with leaf aqueous extracts of the Meliaceae tree Trichilia glabra showed a diminution in both their phagocytic and respiratory burst activities. A decrease in the haemolytic capacity of the human complement was also observed. The significance of the inhibitory effect observed over some components of the human immune system closely related with the inflammatory process is discussed. © 1998 John Wiley & Sons, Ltd.