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Radical scavenging activity and antioxidant properties of tannins from Guiera senegalensis (Combretaceae)
Author(s) -
Bouchet Nathalie,
Barrier Laurence,
Fauconneau Bernard
Publication year - 1998
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/(sici)1099-1573(199805)12:3<159::aid-ptr209>3.0.co;2-c
Subject(s) - gallic acid , dpph , antioxidant , chemistry , scavenger , tannin , hydrolyzable tannin , lipid peroxidation , combretaceae , free radical scavenger , proanthocyanidin , polyphenol , quinic acid , tannic acid , condensed tannin , methyl gallate , biochemistry , traditional medicine , food science , organic chemistry , botany , biology , medicine
The antioxidant properties of nine tannins isolated and characterized from different parts of Guiera senegalensis were evaluated. Interesting results showed that galloylquinic acids (hydrolysable tannins), resulting from a tri‐ or tetra‐substitution of galloyl groups on the quinic acid skeleton, played a crucial role in the inhibitory effect on Fe 2+ ‐induced lipid peroxidation in rat liver microsomes and radical scavenger activity in the 1,1‐diphenyl‐2‐picrylhydrazyl (DPPH) test. The effects of all tannins were markedly higher than that of gallic acid. Condensed tannins such as epicatechin and epigallocatechin gallate also showed fairly significant effects in both tests. © 1998 John Wiley & Sons, Ltd.