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Effect of traditional chinese prescriptions and their main crude drugs on 1,1‐diphenyl‐2‐picrylhydrazyl radical
Author(s) -
Yokozawa Takako,
Chen Cui Ping,
Liu Zhong Wu
Publication year - 1998
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/(sici)1099-1573(199803)12:2<94::aid-ptr194>3.0.co;2-u
Subject(s) - dpph , traditional medicine , radix (gastropod) , medical prescription , chemistry , anti oxidant , pharmacology , traditional chinese medicine , antioxidant , medicine , biochemistry , botany , biology , alternative medicine , pathology
Abstract The inhibitory effects of 79 traditional Chinese prescriptions and 28 crude drugs on the 1,1‐diphenyl‐2‐picrylhydrazyl (DPPH) radical were examined, and many demonstrated significant inhibition. The most effective crude drugs were Gallae Rhois and Rhei Rhizoma, followed in order by Cinnamomi Cortex, Ephedrae Herba, Scutellariae Radix, Perillae Herba, Paeoniae Ruber Radix and Moutan Cortex, while prescriptions composed of one or more of these crude drugs also showed strong free radical scavenging activity. These results predict that traditional Chinese medicines would be promising agents for scavenging free radicals, and for curing diseases related to free radical reactions. © 1998 John Wiley & Sons, Ltd.