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Inhibitory effect of five plant extracts on heart rates of rats
Author(s) -
PérezGutiérrez Salud,
VargasSolís Rosario,
Zavala S. Miguel,
PérezG. Cuauhtemoc,
PérezG. Rosa M.
Publication year - 1998
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/(sici)1099-1573(1998)12:1+<s49::aid-ptr248>3.0.co;2-b
Subject(s) - pharmacognosy , traditional medicine , inhibitory postsynaptic potential , biology , heart rate , folk medicine , medicine , pharmacology , biological activity , in vitro , blood pressure , endocrinology , biochemistry
Abstract Aqueous extracts of Loeselia mexicana , Calendula officinalis , Teloxys graveolens , Oenothera roseae and Castilleja tenuiflora were tested on the heart activity of male Wistar rats. It was found that C. officinalis , T. graveolens , L. mexicana and O. roseae inhibited the heart contractile activity rising to 100% inhibition at doses of 0.3, 0.5, 0.7 and 1.0 mg/mL respectively. However, C. tenuiflora increases the rate of the heart activity at doses from 0.1 to 0.6 mg/mL. © 1998 John Wiley & Sons, Ltd.