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Antidiarrhoeal activity of C‐9 aldehyde isolated from Aloysia triphylla
Author(s) -
Pérez G. Salud,
Zavala S. Miguel A.,
Vargas S. Rosario,
Pérez G. Cuauhtemoc,
Pérez G. Rosa M.
Publication year - 1998
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/(sici)1099-1573(1998)12:1+<s45::aid-ptr246>3.0.co;2-t
Subject(s) - antidiarrhoeal , traditional medicine , verbenaceae , medicine , stereochemistry , chemistry , organic chemistry , castor oil
C‐9 aldehyde was found in Aloysia triphylla essential oil. It was tested on diarrhoeic mice induced with castor oil or magnesium sulphate. It was found that this compound diminished the number of diarrhoeic faeces at doses of 7, 14 and 28 μL. The highest effect was found with 14 μL. Also, the effect of this compound was evaluated on the intestinal transit of rats increased by castor oil. At the dose used, the intestinal transit was delayed in the first 30 min after adminstration of the cathartic agent. © 1998 John Wiley & Sons, Ltd.