Premium
Pharmacological action of aqueous crude extracts of Artemisia verlotorum Lamotte (Compositae)
Author(s) -
Martinotti Enrica,
Calderone Vincenzo,
Breschi Maria Cristina,
Bandini Paola,
Cioni Pier Luigi
Publication year - 1997
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/(sici)1099-1573(199712)11:8<612::aid-ptr167>3.0.co;2-e
Subject(s) - atropine , muscarinic acetylcholine receptor , pharmacognosy , traditional medicine , pharmacology , guinea pig , ileum , chemistry , in vitro , biological activity , biology , medicine , biochemistry , endocrinology , receptor
The pharmacological study of the responses evoked by a dried aqueous extract of Artemisia verlotorum on different guinea‐pig and rat isolated organs in vitro , suggests a possible muscarinic activity as a cause of the antihypertensive activity. The ability of atropine, in ileum preparations, and of N ω ‐nitro L ‐arginine methyl ester, in aortic preparations, to inhibit the plant effects seems to confirm the muscarinic nature of the responses © 1997 John Wiley & Sons, Ltd.