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Effects of extracts of Olax subscorpioides and Aspilia africana on bovine red blood cells
Author(s) -
Oyedapo O. O.,
Akindele V. R.,
Okunfolami O. K.
Publication year - 1997
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/(sici)1099-1573(199706)11:4<305::aid-ptr39>3.0.co;2-9
Subject(s) - pharmacognosy , red blood cell , ethanol , tonicity , lysis , traditional medicine , chemistry , membrane , blood cell , pharmacology , in vitro , biological activity , biochemistry , biology , medicine , immunology
Isosaline and ethanol extracts of Olax subscorpioides and Aspilia africana were investigated for their antiinflammatory properties. Both extracts exhibited antiinflammatory activity by stabilizing bovine red blood cell membranes against heat and hypotonic induced lyses. The ethanol extracts showed a biphasic effect on membrane stabilization at all the concentrations tested. The activities of the extracts were comparable to that of the standard drug indomethacin. © 1997 John Wiley & Sons, Ltd.