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Evaluation of the in vitro antioxidant activity in extracts of Uncaria tomentosa (Willd.) DC.
Author(s) -
Desmarchelier C.,
Mongelli E.,
Coussio J.,
Ciccia G.
Publication year - 1997
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/(sici)1099-1573(199705)11:3<254::aid-ptr76>3.0.co;2-5
Subject(s) - antioxidant , bark (sound) , in vitro , traditional medicine , chemistry , tbars , pharmacognosy , methanol , sugar , biochemistry , biological activity , biology , organic chemistry , medicine , lipid peroxidation , ecology
Different extracts of U. tomentosa were tested in vitro for their antioxidant activity utilizing tert ‐butyl‐hydroperoxide‐initiated chemiluminescence in rat liver homogenates. Methanol fractions of both stem‐bark and roots were capable of exerting antioxidant activity by this technique. The presence of different concentrations of bark and root methanol extracts also prevented TBARS production and free radical‐mediated DNA‐sugar damage. © 1997 John Wiley & Sons, Ltd.