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Cytostatic activity against HEp‐2 cells of methanol extracts from Viscum cruciatum Sieber parasitic on Crataegus monogyna Jacq. and two isolated principles
Author(s) -
Gómez M. A.,
Sáenz M. T.,
García M. D.,
Ahumada M. C.,
De La Puerta R.
Publication year - 1997
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/(sici)1099-1573(199705)11:3<240::aid-ptr54>3.0.co;2-k
Subject(s) - methanol , in vitro , biology , hyperoside , growth inhibition , chemistry , microbiology and biotechnology , biochemistry , organic chemistry , rutin , antioxidant
We have determined the cytostatic activity in vitro against HEp‐2 cells of methanol extracts from V. cruciatum Sieber (Viscaceae) parasitic on C. monogyna Jacq. (Rosaceae), C. monogyna parasitized and C. monogyna . non‐parasitized. The methanol extracts assayed exhibited a moderate degree of growth inhibition compared with the values obtained with the 6‐mercaptopurine (solution used as a positive control). Hyperoside from C. monogyna showed only a low degree of growth inhibition. However, β‐amyrin acetate, from V. cruciatum , exhibited a high degree of growth inhibition compared with the values obtained with the solution used as a positive control. © 1997 John Wiley & Sons, Ltd.