Premium
Effect of garlic and garlic preparations on physiological and psychological stress in mice
Author(s) -
Ushijima Mitsuyasu,
Sumioka Isao,
Kakimoto Masanori,
Yokoyama Koji,
Uda Naoto,
Matsuura Hiromichi,
Kyo Eikai,
Suzuki Ayumi,
Kasuga Shigeo,
Itakura Yoichi,
Petesch Brenda L.,
Amagase Harunobu
Publication year - 1997
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/(sici)1099-1573(199705)11:3<226::aid-ptr85>3.0.co;2-e
Subject(s) - garlic powder , behavioural despair test , traditional medicine , pharmacognosy , food science , allium sativum , medicine , chemistry , biology , raw material , botany , biochemistry , biological activity , in vitro , organic chemistry , hippocampus , antidepressant
The effect of several kinds of garlic preparations such as raw garlic juice (RGJ), heated garlic juice (HGJ), processed garlic powder (PGP) and aged garlic extract (AGE) on both physiological and psychological stress were investigated using four stress models in mice: forced swimming test, mechanical treadmill running, immobilization stress test, and a cooling rewarming test. RGJ was shown to be effective only at a low dose in the forced swimming test, whereas the effect was reduced at a high dosage. HGJ and PGP demonstrated no antistress effects. In contrast, AGE was shown to be effective in all of the stress tests. © 1997 by John Wiley & Sons, Ltd.