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A controlled clinical study of Kanjang mixture in the treatment of uncomplicated upper respiratory tract infections
Author(s) -
Thom Erling,
Wollan Terje
Publication year - 1997
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/(sici)1099-1573(199705)11:3<207::aid-ptr82>3.0.co;2-s
Subject(s) - tolerability , medicine , placebo , respiratory tract infections , clinical trial , upper respiratory tract infection , randomized controlled trial , respiratory tract , respiratory system , anesthesia , adverse effect , alternative medicine , pathology
A randomized, double‐blind placebo‐controlled parallel group clinical trial was performed to investigate the therapeutic effect of Kanjang mixture in the treatment of uncomplicated upper respiratory tract infections (common cold). Sixty‐six patients aged between 18 and 40 years participated. Medication was taken three times daily for a minimum of 5 days or a maximum of 10 days. The primary outcome measures were: the effect on coughing; quality of sleep; mucus discharge in the respiratory tract; nasal congestion; and a global evaluation of the clinical situation and medication tolerability. Assessments were recorded by patients using visual analogue scales 2, 4 and 10 days after the start of treatment. Sixty patients completed the study according to the protocol. The improvement in symptoms following treatment with Kanjang mixture was significantly better on the day 2 and 4 assessments compared with placebo, while the day 10 scores were not significantly different. Tolerability of both treatments was excellent and no side‐effects were reported in either of the two groups. Treatment with the herbal mixture Kangjang significantly eased the symptoms related to uncomplicated upper respiratory tract infections. Combined with the excellent tolerability, Kanjang mixture can be an attractive alternative for the treatment of such ailments. © 1997 John Wiley & Sons, Ltd.