Premium
Antiviral Activity of an Aqueous Extract of the Cyanobacterium Microcystis aeruginosa
Author(s) -
Nowotny A.,
Mentel R.,
Wegner U.,
Mundt S.,
Lindequist U.
Publication year - 1997
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/(sici)1099-1573(199703)11:2<93::aid-ptr46>3.0.co;2-g
Subject(s) - virus , microcystis aeruginosa , aqueous solution , microbiology and biotechnology , influenza a virus , viral replication , pharmacognosy , chemistry , protease , biological activity , biology , virology , aqueous extract , traditional medicine , bacteria , in vitro , biochemistry , enzyme , cyanobacteria , medicine , organic chemistry , genetics
The crude aqueous extract of a field collected strain of Microcystis aeruginosa (Kütz) showed antiviral activity against influenza A virus. The concentration for 50% inhibition of virus replication in MDCK cells was 11 μg dry extract/mL. The virus specific protein synthesis decreased if the extract was present over the whole time of replication. Furthermore protease inhibitory activity was estimated for the crude aqueous extract and subextracts. © 1997 by John Wiley & Sons, Ltd.