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Antidepressant Effects of Ethanol Extract of Areca catechu in Rodents
Author(s) -
Dar Ahsana,
Khatoon Shagufta
Publication year - 1997
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/(sici)1099-1573(199703)11:2<174::aid-ptr65>3.0.co;2-b
Subject(s) - antidepressant , catechu , areca , ethanol , traditional medicine , pharmacognosy , pharmacology , behavioural despair test , chemistry , medicine , biological activity , in vitro , biochemistry , structural engineering , nut , hippocampus , engineering
We report on the antidepressant activity in the ethanol extract of Areca catechu. Antidepressant activity was evaluated in rodents using the forced swimming and tail suspension tests. The ethanol extract (4–80 mg/kg) caused a significant reduction in the immobility time without effecting the spontaneous motor activity. Our findings suggest that the ethanol extract possesses antidepressant activities. © 1997 by John Wiley & Sons, Ltd.