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Effects on Arterial Blood Pressure of Methanol and Dichloromethanol Extracts from Juniperus oxycedrus L.
Author(s) -
Bello R.,
Moreno L.,
Beltrán B.,
PrimoYuacute;fera E.,
Esplugues J.
Publication year - 1997
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/(sici)1099-1573(199703)11:2<161::aid-ptr57>3.0.co;2-c
Subject(s) - blood pressure , medicine , pharmacognosy , traditional medicine , anesthesia , pharmacology , chemistry , biological activity , biochemistry , in vitro
The present study analysed the effect of the methanol and dichloromethanol extracts from Juniperus oxycedrus on arterial blood pressure in anaesthetized rats. The arterial blood pressure of normotensive rats was significantly reduced by the i.v. administration of both extracts. The hypotensive effect of these extracts was independent of the adrenergic system. These results may explain the vasorelaxing actions observed in other Juniperus species. © 1997 by John Wiley & Sons, Ltd.