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A practical and speedy screening method for murine anaphylaxis: On the antianaphylactic effect of Impatiens balsamina L.
Author(s) -
Ishiguro Kyoko,
Fukumoto Hisae
Publication year - 1997
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/(sici)1099-1573(199702)11:1<48::aid-ptr947>3.0.co;2-3
Subject(s) - impatiens , balsaminaceae , traditional medicine , biology , botany , medicine , cultivar
An effective screening method for antianaphylaxis was established using blood pressure (BP) monitoring in unanesthetized mice with an immediate hypersensitivity reaction system induced by hen egg‐white lysozyme (HEL). This method allows speedy and reproducible screening of antianaphylactic substances. Using this system, the antianaphylactic effect was estimated for the 35% ethanol extract (IB) of petals of Impatiens balsamina L. and the compounds isolated from Impatiens balsamina L. © 1997 John Wiley & Sons, Ltd.