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Antimicrobial Activity of Constituents Isolated from Lychnophora salicifolia (Asteraceae)
Author(s) -
Miguel Obdulio G.,
Lima Edeltrudes O.,
Morais Verônica M. F.,
Gomes Sosigenas T. A.,
Delle Monache Franco,
Bella Cruz Alexandre,
Bella Cruz Rosana C.,
Filho Valdir Cechinel
Publication year - 1996
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/(sici)1099-1573(199612)10:8<694::aid-ptr923>3.0.co;2-x
Subject(s) - asteraceae , antimicrobial , traditional medicine , antifungal , antibacterial activity , agar , folk medicine , minimum inhibitory concentration , agar diffusion test , pharmacognosy , biology , medicinal plants , chemistry , biological activity , botany , medicine , microbiology and biotechnology , bacteria , in vitro , biochemistry , genetics
Lychnophora salicifolia (Asteraceae), a native Brazilian medicinal plant used in folk medicine against some diseases, revealed the presence of two known caryophyllene derivatives, in a satisfactory yield: lychnopholic acid 1 and acetyl lychnopholic acid 2. These compounds exhibited antifungal activity by the agar diffusion method, and antibacterial activity by the methods of diffusion and minimum inhibitory concentration (MIC). However, compound 2 was more potent than 1, suggesting that the acetyl group is responsible for antimicrobial activity.