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Extract from Sickingia williamsii Reduces Morphine Withdrawal in vitro
Author(s) -
Capasso A.,
Aquino R.,
Simone F. De,
Sorrentino L.
Publication year - 1996
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/(sici)1099-1573(199611)10:7<622::aid-ptr904>3.0.co;2-c
Subject(s) - morphine , in vitro , pharmacology , traditional medicine , chemistry , medicine , biochemistry
The present study examined the effect of an extract from Sickingia williamsii Standl. (Rubiaceae) on morphine withdrawal in vitro . The extract of S. williamsii (50–100–250 μg\mL organ bath) significantly and in a concentration dependent manner reduced the morphine withdrawal. The results of the present study suggest that this extract may be a potential antiaddictive agent.