Premium
Protective Action of Butanolic Extract of Pueraria tuberosa DC. Against Carbon Tetrachloride Induced Hepatotoxicity in Adult Rats
Author(s) -
Shukla Sangeeta,
Jonathan Sheel,
Sharma Abhilasha
Publication year - 1996
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/(sici)1099-1573(199611)10:7<608::aid-ptr842>3.0.co;2-1
Subject(s) - carbon tetrachloride , ccl4 , pharmacology , phytotherapy , traditional medicine , medicine , chemistry , pathology , organic chemistry , alternative medicine
Administration of CCl 4 at a dose of 0.1 mL/kg/day for 7 days to normal rats provoked significant alterations in the various biochemical variables. It also caused severe histopathological lesions. Priming with the butanol extract of P. tuberosa or conjoint administration of extract along with CCl 4 , provided significant protection against CCl 4 induced injury.