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Antidermatophytic Action of the Essential Oil of Chenopodium ambrosioides and an Ointment Prepared from it
Author(s) -
Kishore N.,
Chansouria J. P. N.,
Dubey N. K.
Publication year - 1996
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/(sici)1099-1573(199608)10:5<453::aid-ptr874>3.0.co;2-a
Subject(s) - trichophyton , fungicide , chenopodium , microsporum , traditional medicine , dermatophyte , essential oil , broad spectrum , biology , medicine , botany , chemistry , microbiology and biotechnology , antifungal , combinatorial chemistry , weed
Abstract The essential oil from the leaves of Chenopodium ambrosioides exhibited antimycotic activity against the dermatophytes Trychophyton mentagrophytes and Microsporum audouinii , at a concentration of 50 ppm. Its nature was fungicidal and it exhibited a broad antimycotic spectrum against dermatophytes. The shelf‐life of chenopodium oil was found to be 360 days. The ointment of the oil prepared in petroleum jelly could control established ringworm infection in guinea‐pigs during preliminary animal trials.