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Antilipid Peroxidative Property of Shilajit
Author(s) -
Tripathi Yamini B.,
Shukla Savita,
Chaurasia Savita,
Chaturvedi Shashikant
Publication year - 1996
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/(sici)1099-1573(199605)10:3<269::aid-ptr817>3.0.co;2-3
Subject(s) - lipid peroxidation , cumene hydroperoxide , glutathione , incubation , chemistry , biochemistry , antioxidant , pharmacology , enzyme , biology , catalysis
We have investigated the effect of shilajit on lipid peroxidation and glutathione content in rat liver homogenate. It inhibited lipid peroxidation induced by cumene hydroperoxide and ADP/Fe ++ complex in a dose dependent manner. It also reduced the rate of oxidation of reduced glutathione content and inhibited ongoing lipid peroxidation, induced by these agents immediately after its addition to the incubation system.