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Estimation of Cardiac Depressant Activity of Ten Medicinal Plant Extracts from Pakistan
Author(s) -
Sajid Tasneem Mariam,
Rashid Shahid,
Ahmad Mansoor,
Khan Usmanghani
Publication year - 1996
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/(sici)1099-1573(199603)10:2<178::aid-ptr802>3.0.co;2-t
Subject(s) - traditional medicine , chronotropic , verbenaceae , medicinal plants , apocynaceae , biology , medicine , heart rate , blood pressure , endocrinology
Ten medicinal plants extracts were pharmacologically screened for their cardiac activity on isolated rabbit heart, and showed significant negative inotropic activity with negative chronotropic effects. In all cases alcohol dried extracts were used and reconstituted in either water or ethyl acetate for these tests. The plant extracts which produced cardiac depression were Cactus grandiflora , Carissa carandas Linn., Duranta repens Linn., Eclipta prostrata Roxb., Heliotropium ophioglossum , Prosopis glandulosa , Scheweinfurthia sphaerocarpa A. Br., Solanum surattense Burm. f., Tephrosia uniflora Pers., Nardostachys jatamansi Dc. (Syn. Valeriana jatamansi ).