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Fertility Suppression of the Male Mouse after Administration of Mint Leaf Extract
Author(s) -
Sharma Nidhi,
Jacob Dennis
Publication year - 1996
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/(sici)1099-1573(199603)10:2<175::aid-ptr800>3.0.co;2-7
Subject(s) - mentha arvensis , biology , acid phosphatase , mating , libido , fertility , alkaline phosphatase , ratón , reproduction , botany , andrology , traditional medicine , endocrinology , biochemistry , medicine , enzyme , population , genetics , environmental health , essential oil
The antifertility effect of an aqueous extract of mint ( Mentha arvensis ) leaves was observed on male albino mice after administration of 10, 5 and 2 mg of the extract every alternate day for 20 days. At the tried experimental protocol, a dose related decrease in the reproductive organ weights was recorded. A marked alteration in the phosphatase content in the reproductive organs was also obtained. While the acid phosphatase mean level recorded a marked decrease, the alkaline phosphatase content of the reproductive organs exhibited a statistically significant increase. Mating performance and libido of the males treated with the mint leaf extract at all the three tried doses was not altered but mating with fertile proestrus females proved to be sterile in each case.