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Evaluation of the Antioxidant and Antiviral Actions of Herbal Preparations: Rovital and Carciverin V (C1983)
Author(s) -
Aruoma Okezie I.,
Halliwell Barry,
Mahmood Naheed,
Burke Andrew,
Greenspan Howard C.
Publication year - 1996
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/(sici)1099-1573(199603)10:2<152::aid-ptr794>3.0.co;2-0
Subject(s) - antioxidant , elastase , lipid peroxidation , chemistry , bleomycin , liposome , pharmacognosy , pharmacology , biochemistry , biological activity , traditional medicine , in vitro , biology , medicine , enzyme , chemotherapy , genetics
The antioxidant and antiviral actions of the herbal extracts Rovital and Carciverin‐V (C1983) were assessed. Solutions of Rovital and C1983 are powerful scavengers of hydroxyl radicals. Rovital did not inhibit DNA damage by bleomycin or copper‐phenanthroline systems, whereas C1983 inhibited moderately. C1983 had significant inhibitory effects on the peroxidation of phospholipid liposomes whereas Rovital did not. However, Rovital and C1983 also interfered with the ability of α 1 ‐antiproteinase to inhibit elastase. The extracts exhibited anti‐HIV activity in C8166 cells at very low concentrations but were also cytotoxic.