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A study on the glycaemic balance in streptozotocin‐diabetic rats treated with an aqueous extract of Ficus carica (fig tree) leaves
Author(s) -
Pérez C.,
Domínguez E.,
Ramiro J. M.,
Romero A.,
Campillo J. E.,
Torres M. D.
Publication year - 1996
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/(sici)1099-1573(199602)10:1<82::aid-ptr776>3.0.co;2-r
Subject(s) - carica , streptozotocin , ficus , aqueous extract , diabetes mellitus , medicine , traditional medicine , pharmacognosy , oral administration , insulin , intraperitoneal injection , moraceae , body weight , pharmacology , endocrinology , biological activity , chemistry , botany , biology , biochemistry , in vitro
The hypoglycaemic effect of an aqueous extract of Ficus carica leaves was studied in streptozotocin‐diabetic rats. The extract induced a significant hypoglycaemic effect after either oral‐ or intraperitoneal (i.p.) administration. Body weight loss was prevented in treated diabetic rats and the survival index was significantly affected by plasma insulin levels. Results show that Ficus carica aqueous extract has a clear hypoglycaemic activity in treated versus non‐treated diabetic rats. The mechanism involved in such an effect is not elucidated.