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Extraction of low‐polarity compounds (with emphasis on coumarin and kaurenoic acid) from Mikania glomerata (‘guaco’) leaves
Author(s) -
Vilegas Janete H. Y.,
de Marchi Ederson,
Lancas Fernando M.
Publication year - 1997
Publication title -
phytochemical analysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 72
eISSN - 1099-1565
pISSN - 0958-0344
DOI - 10.1002/(sici)1099-1565(199709/10)8:5<266::aid-pca363>3.0.co;2-q
Subject(s) - maceration (sewage) , chemistry , chromatography , hexane , supercritical fluid extraction , coumarin , extraction (chemistry) , sonication , lupeol , terpene , yield (engineering) , organic chemistry , metallurgy , materials science , composite material
Five methods for the extraction of low‐polarity compounds from Mikania glomerata Spreng. (Compositae) leaves were compared: conventional maceration, maceration with sonication, Soxhlet, and supercritical fluid extraction using hexane (SFE‐hexane) or carbon dioxide (SFE‐CO 2 ) as the extraction fluid. Evaluation of these methods by relating extraction yield to extraction time showed that SFE‐hexane was the most efficient method. SFE‐CO 2 showed a lower yield, but significantly higher than conventional methods (maceration and Soxhlet). SFE‐hexane and maceration gave the highest yield of coumarin, while maceration under sonication gave the highest yield of kaurenoic acid. Among the further chemical constituents of Mikania glomerata leaves identified by high resolution gas chromatography–mass spectrometry were lupeol and lupeol acetate. © 1997 John Wiley & Sons, Ltd.