Premium
Comparison of supercritical carbon dioxide extraction with solvent extraction of nonacosan‐10‐ol, α‐amyrin acetate, squalene and stigmasterol from medicinal plants
Author(s) -
Choi Young Hae,
Kim Jinwoong,
Noh Min Jeong,
Choi Eun Sun,
Yoo KiPung
Publication year - 1997
Publication title -
phytochemical analysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 72
eISSN - 1099-1565
pISSN - 0958-0344
DOI - 10.1002/(sici)1099-1565(199709/10)8:5<233::aid-pca369>3.0.co;2-k
Subject(s) - supercritical carbon dioxide , chemistry , stigmasterol , extraction (chemistry) , squalene , chromatography , supercritical fluid , supercritical fluid extraction , phytochemical , hexane , solvent , carbon dioxide , organic chemistry , biochemistry
Supercritical carbon dioxide extraction was carried out in the temperature range 35 to 60°C and from 10 to 30 MPa in order to obtain phytochemical components from several medicinal plants. These were nonacosan‐10‐ol (1) from the aerial parts of Ephedra sinica , α‐amyrin acetate (2) from the root bark of Morus alba, and squalene (3) and stigmasterol (4) from the entire plant of Spirodela polyrhiza. For comparison, Soxhlet extraction with n ‐hexane was also carried out for these constituents. In the case of supercritical carbon dioxide extraction of 1, 2 and 4, the extraction yields tended to increase with increased temperature when the pressure was above 20 MPa. However, extraction yields were maximal at 40°C or 50°C below 15 MPa. When the amounts of extracts obtained by supercritical extraction are compared with those by Soxhlet extraction using n ‐hexane, it is apparent that supercritical carbon dioxide extraction can be used as an alternative method in the case of squalene and nonacosan‐10‐ol. © 1997 John Wiley & Sons, Ltd.