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Analytical Supercritical Fluid Extraction of Natural Products
Author(s) -
Modey William K.,
Mulholland Dulcie A.,
Raynor Mark W.
Publication year - 1996
Publication title -
phytochemical analysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 72
eISSN - 1099-1565
pISSN - 0958-0344
DOI - 10.1002/(sici)1099-1565(199601)7:1<1::aid-pca275>3.0.co;2-u
Subject(s) - chemistry , supercritical fluid extraction , chromatography , supercritical fluid chromatography , supercritical fluid , extraction (chemistry) , supercritical carbon dioxide , matrix (chemical analysis) , solubility , sample preparation , adsorption , gas chromatography , organic chemistry
Supercritical fluid extraction (SFE) is a rapid, selective and convenient method for sample preparation prior to the analysis of compounds in natural product matrices. SFE is usually performed with pure or modified carbon dioxide, which facilitates off‐line collection of extracts and on‐line coupling with other analytical methods such as gas and supercritical fluid chromatography. A number of factors influence extraction yields, these being solubility of the solute in the fluid, diffusion through the matrix and adsorption processes in the matrix. A wide range of applications is described for the extraction of carotenoids, lipids, flavour and fragrance compounds, steroids and triterpenes, alkaloids and mycotoxins.

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