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Feasibility study of lactate imaging of head and neck tumors
Author(s) -
Adalsteinsson E.,
Spielman D. M.,
Pauly J. M.,
Terris D. J.,
Sommer G.,
Macovski A.
Publication year - 1998
Publication title -
nmr in biomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.278
H-Index - 114
eISSN - 1099-1492
pISSN - 0952-3480
DOI - 10.1002/(sici)1099-1492(1998110)11:7<360::aid-nbm518>3.0.co;2-p
Subject(s) - head and neck , nuclear medicine , nuclear magnetic resonance , medicine , chemistry , physics , surgery
A proton spectroscopic imaging sequence was used to investigate the feasibility of lactate imaging in head and neck tumors. The sequence employs a two‐shot lactate editing method with inversion recovery for additional lipid suppression, and a restricted field of view to suppress motion artifacts. Variations in acquisition parameters and two different receive coils were investigated on twelve patients. Elevated lactate was detected in three patients, no lactate was observed in seven patients, and two studies were inconclusive because of severe motion or inhomogeneity artifacts. Best results were obtained with an anterior/posterior neck coil at a 288 ms echo time (TE). © 1998 John Wiley & Sons, Ltd.