Premium
Force of Voluntary Exercise does not Affect Sensorimotor Cortex Activation as Detected by Functional MRI at 1.5 T
Author(s) -
Ludman C. N.,
Cooper T. G.,
PloutzSynder L. L.,
Potchen E. J.,
Meyer R. A.
Publication year - 1996
Publication title -
nmr in biomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.278
H-Index - 114
eISSN - 1099-1492
pISSN - 0952-3480
DOI - 10.1002/(sici)1099-1492(199608)9:5<228::aid-nbm420>3.0.co;2-1
Subject(s) - voxel , somatosensory system , motor cortex , cortex (anatomy) , neuroscience , sensorimotor cortex , physical medicine and rehabilitation , medicine , psychology , stimulation , radiology
Echo‐planar brain images (1.5 T, 1‐shot GRE, TR/TE =3000/45) were acquired during 30–60 s cycles of repetitive (1.3–1.7 Hz) finger flexion exercise against light (0.24) vs heavy (1.40 kg) weights. In protocols during which exercise was alternated with periods of rest, active voxels were identified in the contralateral motor and somatosensory areas by cross‐correlation against an on–off waveform. However, there was no significant difference between the responses to light vs heavy weights. In a continuous repetitive exercise protocol, in which only the weights were cycled, no force‐correlated voxels were identified. Inasmuch as force‐correlated neurons are known to be present in the primate cortex, the results illustrate a potential limitation of functional MRI studies based on the BOLD effect.