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Acid–base equilibria in Mannich bases assessed by UV absorption spectroscopy
Author(s) -
Przes<?tot=.pt> <?toc=Black>ł<?toc> <?tot>awska M.,
Koll A.,
Witanowski M.
Publication year - 1999
Publication title -
journal of physical organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.325
H-Index - 66
eISSN - 1099-1395
pISSN - 0894-3230
DOI - 10.1002/(sici)1099-1395(199906)12:6<486::aid-poc144>3.0.co;2-3
Subject(s) - chemistry , protonation , intramolecular force , aqueous solution , mannich base , dissociation constant , acid dissociation constant , dissociation (chemistry) , absorption spectroscopy , phenol , computational chemistry , base (topology) , stereochemistry , organic chemistry , ion , mathematical analysis , biochemistry , physics , receptor , mathematics , quantum mechanics
Acid–base equilibria in selected o ‐methylamino‐ N ‐dialkylphenols in aqueous solutions are discussed. Analysis of the pH dependence of the UV absorption spectra with application of the multi‐channel least‐squares procedure allows the estimation of some microscopic dissociation constants. Results are discussed on the basis of intramolecular interactions between different substituents in phenol rings and protonation of the methylamino groups in amino acids. Copyright © 1999 John Wiley & Sons, Ltd.