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Selective formation of glycylglycine by dehydration of glycine adsorbed on silica gel
Author(s) -
Ogawa Haruo,
Fujigaki Tamiki,
Chihara Teiji
Publication year - 1999
Publication title -
journal of physical organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.325
H-Index - 66
eISSN - 1099-1395
pISSN - 0894-3230
DOI - 10.1002/(sici)1099-1395(199904)12:4<354::aid-poc157>3.0.co;2-d
Subject(s) - glycylglycine , chemistry , dehydration , glycine , silica gel , adsorption , organic chemistry , polymer chemistry , amino acid , biochemistry
Silica gel promotes the selective dehydration of glycine to form intermediate glycylglycine, with inhibition of the formation of stable glycine anhydride and polymer products. IR measurements indicate that glycine adsorbed on silica gel results in the formation of neutral species having CO and NH 2 groups. The species is considered to stimulate dehydration, leading to the reported selective dehydration. Copyright © 1999 John Wiley & Sons, Ltd.