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Design, synthesis and antimycotic activity of ( N ‐heteroaryl)arylmethanamines
Author(s) -
Ballistreri Alberto,
Bottino Alessandra,
Musumarra Giuseppe,
Fioravanti Rossella,
Biava Mariangela,
Porretta Giulio Cesare,
Simonetti Nicola,
Villa Adelaide
Publication year - 1996
Publication title -
journal of physical organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.325
H-Index - 66
eISSN - 1099-1395
pISSN - 0894-3230
DOI - 10.1002/(sici)1099-1395(199602)9:2<61::aid-poc748>3.0.co;2-r
Subject(s) - chemistry , quinoline , stereochemistry , antifungal , amine gas treating , combinatorial chemistry , aromatic amine , organic chemistry , microbiology and biotechnology , biology
The design, synthesis and antimycotic activities of 18 ( N ‐heteroaryl)arylmethanamines are reported. The MIC against Candida strains of the most active amine, 3‐(p‐methylbenzylamino)quinoline, is comparable to that of pyrrolnitrin.