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A facile synthesis of 2,5‐dimethyl‐4‐hydroxy‐3(2 H )‐furanone [2‐ (or 5‐) methyl 14 C] (furaneol [2‐ (or 5‐) methyl 14 C])
Author(s) -
Roscher René,
Schreier Peter,
Schwab Wilfried
Publication year - 1997
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/(sici)1099-1344(199706)39:6<493::aid-jlcr990>3.0.co;2-f
Subject(s) - chemistry , organic chemistry
A convenient one‐step synthesis of 14 C‐labelled 2,5‐dimethyl‐4‐hydroxy‐3(2 H )‐furanone (furaneol) was accomplished by a piperidine acetate catalyzed Maillard‐type reaction of commercially available fucose L‐[1‐ 14 C]. This important aroma compound found in strawberry fruits, obtained in ≥ 90 % radiochemical purity, should prove useful in in‐vivo metabolism studies. © 1997 John Wiley & Sons, Ltd.