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Synthesis of [ 3 H‐pyroglutamyl 1 ]‐adipokinetic hormone‐1
Author(s) -
Starratt A. N.,
King L. E.,
Loughton B. G.
Publication year - 1996
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/(sici)1099-1344(199612)38:12<1139::aid-jlcr932>3.0.co;2-2
Subject(s) - pyroglutamic acid , chemistry , adipokinetic hormone , hormone , glutamine , biochemistry , specific activity , stereochemistry , amino acid , enzyme , neuropeptide , receptor
L‐[3,4‐ 3 H(N)]‐Glutamine was cyclized to [ 3 H]‐pyroglutamic acid and coupled with [des‐pGlu 1 ]‐AKH‐I to give [ 3 H‐pyroglutamyl 1 ]‐adipokinetic hormone‐I with a specific activity of 46 Ci/mmole. Results relating to stability of this product during storage are reported.