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Synthesis of 2‐phenyl‐1,2‐benziso[ 77 Se]selenazol‐3(2H)‐one: “Ebselen”
Author(s) -
Oppenheimer Jossian,
Silks Louis A.
Publication year - 1996
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/(sici)1099-1344(199603)38:3<281::aid-jlcr833>3.0.co;2-1
Subject(s) - chemistry , ebselen , yield (engineering) , selenium , combinatorial chemistry , organic chemistry , glutathione , glutathione peroxidase , enzyme , materials science , metallurgy
Abstract Synthesis of 2‐Phenyl‐1,2‐benziso[ 77 Se]selenazol‐3(2H)‐one has been accomplished in one step from 94% 77 Se and commercially available starting materials in 76% yield based on the enriched elemental selenium.